Official websites use. Share sensitive information only on official, secure websites. Multimorbidity becomes more prevalent in patients admitted for acute myocardial infarction AMI. We investigated the association of an increasing number of comorbidities with the excess risk of in-hospital mortality and other clinically outcomes in hospitalized AMI patients.
In this population-based cohort study, we analyzed ' admissions for AMI between and in Switzerland. We stratified patients based on four different age categories and investigated the association of the number of five common comorbidities diabetes, chronic kidney-, chronic obstructive pulmonary-, cerebrovascular-, and peripheral artery disease and risk of in-hospital mortality and other outcomes.
A total of 5' admitted AMI patients 4. We found a stepwise increase in mortality risk with each additional comorbidity. Again, the association of the numbers of prevalent comorbidities with adverse outcomes was strongest in the youngest patient population.
In patients with AMI, the burden of comorbidities has a strong association with in-hospital mortality and other adverse outcomes โ especially in younger patients. As the western population is aging, multimorbidity gains increasing importance with significant health care implications [2] , [3]. Beside patients, also physicians and hospitals are extensively challenged to overcome this burden of multimorbidity [4].
Whereas the majority of multimorbid patients are older, there is cumulative evidence that even younger patients are progressively confronted with multiple chronic disease conditions [5]. Younger comorbid patients with two, three or more chronic diagnoses are at higher risk for adverse outcomes [5].
