Official websites use. Share sensitive information only on official, secure websites. This is an open access article distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. To quantify and describe flare-ups of house dust mite allergic rhinitis HDM-AR which had occurred during the last 12 months in a population of adults and children candidate for Allergen ImmunoTherapy AIT.
Next, to identify associated clinical features. Flare-ups were all period with impairment of quality of life QoL and requiring a change in their usual treatment.
Data were collected using medical records and patient questionnaires. Severe and persistent AR affected Asthma was associated with AR in The occurrence of at least one AR flare-up in the year was reported by Deeply or moderately AR-related degraded QoL was experienced by AR flare-ups are frequent and impair QoL in HDM-allergic patients, suggesting that it could be considered as therapeutic targets.
It is often associated with asthma [ 4 , 5 ] and both allergic reactions have their own medical history and interactions [ 6 , 7 ]. Although it is well known that asthma can be uncontrolled, leading to emergency visits, hospitalizations, intensive care and unfortunately sometimes death, AR is perceived as a mild benign disease without hospitalization and death.
However, AR patients present impaired quality of life QoL to the same extent as asthma patients [ 8 — 10 ]. While asthma therapeutic strategy is primarily aimed at achieving control of symptoms and reducing number of exacerbations, the AR strategy is to control symptoms and improve QoL [ 11 ]. Until now, it is difficult to know whether in the history of AR, flare-ups are observable in the same way as for asthma notably when the former is persistent and severe.
